Rabbit Secondary Antibodies
Cayman Chemical PDL1CD274CTerm RabbIt M 100uL
A quaternary ammonium-containing cationic surfactant with diverse biological activities an inhibitor of F. tularensis AcpB (Ki 0.59 UM) and C. albicans V-ATPase (EC50 69 UM) inhibits osteoclastogenesis RANKL-induced osteoclastogenesis in BMDMs inhibits bone resorption by mature osteoclasts at 100 and 200 nM prevents LPS-induced bone loss in a calvarial osteolytic mouse model at 5 mg/kg per day induces mortality in C. oncophora O. ostertagi H. contortus and T. circumcincta (EC50s 4.5 10.8 5.1 and 6.7 UM respectively) but is cytotoxic to HEK293 and RAW 264.7 cells (CC50s 9.2 and 5.7 UM respectively)
ABclonal Technology Mitofilin Rabbit mAb
Enables RNA binding activity Involved in cristae formation Located in mitochondrial inner membrane Part of MICOS complex
ABclonal Technology TSLP Rabbit mAb
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c( ) dendritic cells The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases including asthma allergic inflammation and chronic obstructive pulmonary disease The protein is therefore considered a potential therapeutic target for the treatment of such diseases In addition the shorter (predominant) isoform is an antimicrobial protein displaying antibacterial and antifungal activity against B cereus E coli E faecalis S mitis S epidermidis and C albicans Alternative splicing of this gene results in multiple transcript variants
Cayman Chemical FOXP1CTerm RabbIt Monclo 100uL
A pyrimidine analog and nitrosourea alkylating agent inhibits the growth of U-251MG and EA285 glioma cells at 10 g/ml increases the median survival time in a Walker 256 carcinoma rat model of metastatic brain tumors at 30 mg/kg
ABclonal Technology CYP11A1 Rabbit mAb
This gene encodes a member of the cytochrome P450 superfamily of enzymes The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone the first and rate-limiting step in the synthesis of the steroid hormones Two transcript variants encoding different isoforms have been found for this gene The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide
ABclonal Technology MAVS Rabbit mAb
This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral innate immunity
Cayman Chemical NCAM1CD56CTerm RabbIt Mo 100uL
A catechol estrogen and minor metabolite of estrogen production is increased in microsomes prepared from human mammary adenocarcinoma and fibroadenoma microsomes compared with microsomes prepared from non-cancerous tissues induces renal tumor formation in male hamsters at 25 mg/animal
Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure F(ab')2 Fragment Rabbit Anti-Mouse IgG Fcγ Fragment Specific (min X Hu Sr Prot)
Rhodamine Red-X-AffiniPure F(ab')2 Fragment Rabbit Anti-Mouse IgG Fcγ Fragment Specific (min X Hu Sr Prot)
Cayman Chemical EGFRL858R RabbIt MoncLNal A
A dual agonist of FXR and PPAR activates FXR and PPAR in reporter assays using HEK293T cells (EC50s 0.94 and 1.5 UM respectively) selective for these receptors over RARa RXRa PPARa PPARY and LXRa at 10 UM
ABclonal Technology CYP3A4 Rabbit mAb
This gene encodes a member of the cytochrome P450 superfamily of enzymes The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents This enzyme is involved in the metabolism of approximately half the drugs in use today including acetaminophen codeine cyclosporin A diazepam erythromycin and chloroquine The enzyme also metabolizes some steroids and carcinogens This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21 1 Previously another CYP3A gene CYP3A3 was thought to exist however it is now thought that this sequence represents a transcript variant of CYP3A4 Alternatively spliced transcript variants encoding different isoforms have been identified
United States Biological Corporation RABBIT ANTI-SLC15A3 ID SLC15
NC3245810 RABBIT ANTI-SLC15A3 ID SLC15
ABclonal Technology PE Rabbit anti-Mouse IgM mAb
Enables several functions including antigen binding activity identical protein binding activity and immunoglobulin receptor binding activity Acts upstream of or within several processes including early endosome to late endosome transport immunoglobulin mediated immune response and positive regulation of B cell proliferation Located in external side of plasma membrane extracellular space and perinuclear region of cytoplasm Part of B cell receptor complex and immunoglobulin complex circulating Is expressed in several structures including brain hemolymphoid system and liver Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus Human ortholog(s) of this gene implicated in agammaglobulinemia Orthologous to human IGHM (immunoglobulin heavy constant mu)
ABclonal Technology PE Rabbit anti-Mouse IgM mAb
Enables several functions including antigen binding activity identical protein binding activity and immunoglobulin receptor binding activity Acts upstream of or within several processes including early endosome to late endosome transport immunoglobulin mediated immune response and positive regulation of B cell proliferation Located in external side of plasma membrane extracellular space and perinuclear region of cytoplasm Part of B cell receptor complex and immunoglobulin complex circulating Is expressed in several structures including brain hemolymphoid system and liver Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus Human ortholog(s) of this gene implicated in agammaglobulinemia Orthologous to human IGHM (immunoglobulin heavy constant mu)
Cayman Chemical RabbIt ntI-HA IgGSureLIght 1ea
Rabbit Anti-HA (Hemagglutinin) IgG conjugated to SureLight APC Antibody: Rabbit polyclonal Anti-HA (Hemagglutinin) (YPYDVPDYA) IgG Dye: SureLight™ Allophycocyanin (APC) Excitation max. λ: 652 nm Emission max. λ: 657.5 nm Uses: Flow cytometry/Fluorescence-activated cell sorting, High-throughput screening, Time-resolved fluorescence energy transfer